Vanderbilt University Medical Center Sr. Research Specialist - Clinical Pharmacology in Nashville, Tennessee

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Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery and patient care, VUMC is a community of individuals who come to work each day with the simple aim of changing the world. It is a place where your expertise will be valued, your knowledge expanded and your abilities challenged. It is a place where your diversity — of culture, thinking, learning and leading — is sought and celebrated. It is a place where employees know they are part of something that is bigger than themselves, take exceptional pride in their work and never settle for what was good enough yesterday. Vanderbilt’s mission is to advance health and wellness through preeminent programs in patient care, education, and research.

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This is a full-time, exempt term position lasting six months to one year.

JOB SUMMARY:

Our research group employs cellular and mouse models to study basic mechanisms that promote susceptibility to atrial fibrillation, the most common cardiac arrhythmia. Currently, we are using molecular, biochemical, and functional approaches, including quantitative immunohistochemistry, in mouse models of human disease to investigate the role of reactive lipid mediators and protein oligomers in the arrhythmia substrate. We are seeking a Senior Research Specialist with a prior experience in standard molecular biology, biochemical, and imaging methods and a history of job stability to join our team.

KEY RESPONSIBILITIES:

The person holding this position will be responsible for performing a variety of experiments within a dynamic and interactive environment. Responsibilities will include but are not limited to:

  • In an independent manner, to oversee research projects and perform near to totally independent research; supervise, plan, design and implement research projects; establish protocols; develop and optimize new methods based on literature review; train and supervise technical staff, medical and graduate students. (29%)

  • Shared participation in laboratory operation and inventory is expected such as stocking lab supplies, preparing reagents and buffers for general lab use, performing chemical and radioactive waste disposal, and developing methods and procedures for operation of complex scientific equipment. (10%)

  • Perform standard calculations (involving molarities, % solutions, serial dilutions) and statistical analysis of experimental results. (1%)

  • Perform quantitative immunohistochemistry using established methods, as well as confocal microscopy imaging and data analysis. (20%)

  • Perform flow cytometry experiments using atrial cardiomyocytes and maintain cell cultures. (5%)

  • Recognize experimental problems and optimization of protocols as needed. (5%)

  • Provide support for maintenance of mouse breeding colonies, including DNA isolation and genotyping. (20%)

  • Prepare reports of results, graphs, charts, tables, etc. of research findings.

  • Train and supervise undergraduate, medical and graduate students and other lab members, and supervise their activities. (10%)

Individuals who apply should be capable of following through on lists of assigned tasks, self-starters with an orientation for details and capable of keeping meticulous records. Candidates should already have broad computer skills: Microsoft Word, Excel, PowerPoint, Adobe Photoshop, and statistical analysis, as well as use of Internet for literature and protocol identification. The successful candidate will be a responsible, hard-working and organized individual with good communication skills and careful attention to detail. Prior experience in the requisite experimental techniques is strongly preferred.

VUMC Recent Accomplishments

Because we are committed to providing the best in patient care, education and research, we are proud of our recent accomplishments:

  • US News & World Report: #1 Hospital in Tennessee, #1 Health Care Provider in Nashville, #1 Audiology ( Bill Wilkerson Center at http://www.vanderbilthealth.com/billwilkerson/ ), 12 adult and 10 pediatric clinical specialties ranked among the nation's best, #15 Education and Training

  • Truven Health Analytics: among the top 50 cardiovascular hospitals in the U.S.

  • Becker's Hospital Review: one of the "100 Greatest Hospitals in America"

  • The Leapfrog Group: grade "A" in Hospital Safety Score

  • National Institutes of Health: among the top 10 grant awardees for medical research in the US

  • Magnet Recognition Program: Vanderbilt nurses are the only group honored in Tennessee

  • Nashville Business Journal: Middle Tennessee's healthiest employer

  • American Hospital Association: among the 100 "Most Wired" medical systems in the US

This position requires a Bachelor's degree and 7 years of experience.

Physical Requirements/Strengths needed & Physical Demands:

Movement

  • Occasional: Sitting: Remaining in seated position

  • Occasional: Standing: Remaining on one's feet without moving.

  • Occasional: Walking: Moving about on foot.

  • Occasional: Lifting under 35 lbs: Raising and lowering objects under 35 lbs from one level to another

  • Occasional: Push/Pull: Exerting force to move objects away from or toward.

  • Occasional: Bending/Stooping: Trunk bending downward and forward by bending spine at waist requiring full use of lower extremities and back muscles

  • Occasional: Reaching below shoulders: Extending arms in any direction below shoulders.

  • Occasional: Handling: Seizing, holding, grasping, turning or otherwise working with hand or hands.

Sensory

  • Occasional: Vision: Clarity of near vision at 20 inches or less and far vision at 20 feet or more with depth perception, peripheral vision, color vision.

  • Frequent: Noise: May include exposure to occupational noise levels which equal or exceed an 8-hr time-weighted average of 85 decibels, requiring enrollment in VUMC's Hearing Conservation Program which includes training, use of hearing protection, and periodic audiometry.

  • Continuous: Communication: Expressing or exchanging written/verbal/electronic information.

Environmental Conditions

Job Research

Organization: Clinical Pharmacology-DOM 104342

Title: Sr. Research Specialist - Clinical Pharmacology

Location: TN-Nashville-Preston Cancer Research Building

Requisition ID: 1808683

Vanderbilt University Medical Center is committed to principles of equal opportunity and affirmative action.